Slow synaptic transmission in frog sympathetic ganglia

Slow synaptic transmission in frog sympathetic ganglia.

Bullfrog ganglia contain two classes of neurone, B and C cells, which receive different inputs and exhibit different slow synaptic potentials. B cells, to which most effort has been directed, possess slow and late slow EPSPs. The sEPSP reflects a muscarinic action of acetylcholine released from boutons on B cells, whereas the late sEPSP is caused by a peptide (similar to teleost LHRH) released ...

Synaptic Transmission at Single Boutons in Sympathetic Ganglia.

Synaptic transmission has traditionally been studied at the level of the entire nerve terminal rather than at one of its constituent boutons. Autonomic ganglia provide preparations for recording from individual boutons, as well as for determining the calcium transients necessary for transmitter release at these boutons. The results suggest a new paradigm for synaptic transmission.

Modulation of Synaptic Amplification in Sympathetic Ganglia

Synaptic specificity in frog sympathetic ganglia during reinnervation, sprouting, and embryonic development.

B cells and C cells in frog lumbar sympathetic ganglia are specifically innervated by preganglionic B fibers and C fibers, respectively. To explore the mechanisms underlying the formation of these specific synapses, electrophysiological studies were made of sprouting and regenerating synaptic connections following interruption of the preganglionic pathways. Studies were also made of developing ...

Release-Activated Ca2+ Transport in Neurons of Frog Sympathetic Ganglia

Frog sympathetic ganglion neurons exhibit a novel Ca2+ uptake mechanism, release-activated calcium transport or RACT, which is manifest in both cytosolic and store [Ca2+] signals as greatly accelerated Ca2+ uptake after Ca2+ release from internal stores. RACT is activated by Ca2+ release but not by Ca2+ entry and serves to selectively refill Ca2+ stores after release. RACT lowers cytosolic [Ca2...